The Ultimate Guide To https://www.ceesdekker.net
The Ultimate Guide To https://www.ceesdekker.net
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Halfway as a result of his vocation, Cees Dekker reinvented himself. Just after decades of hardcore physics, he shifted his emphasis to ‘nanobiology’ for the convert with the millennium. A term he coined himself, for a make a difference of reality.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and 1st ever review in the dynamics DNA supercoils and the invention of supercoil hopping
Microbiology has only existed for a century, because we started to research micro-organisms extra seriously. I thought nanobiology was an suitable term, since all molecular biological pertinent interactions happen on the nanoscale: a protein is a number of nanometres in dimensions, DNA is two nm thick.’
‘To start with we checked out biological techniques which has a physical check out and acted on The premise from the equipment we realized. It took a few years just before we started off Doing the job much more on the large Organic challenges. I then started to contact it nanobiology, a phrase that didn't exist at enough time.
2011, initial in vitro measurements of transport throughout one biomimetic nuclear pore advanced; progress of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination
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Incredibly awesome, but that wasn’t genuinely where my curiosity lay. I planned to pioneer And that i had the feeling which was now not feasible, since the most appealing fundamental insights had previously been uncovered. But my industry had produced quite a few exciting new equipment to evaluate particular person molecules. I decided that I desired to implement this to biology, to have a look at it from the physical perspective.’
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Nanoscientist Cees Dekker can be https://www.ceesdekker.net an amiable and flamboyant male who seems Significantly more youthful compared to the sixty two yrs he in fact is – trendy glasses, psychedelic shirt, partaking smile – but not 1 to squander time. He can take his time, but no more than essential.
Such as, we consider the nucleopore sophisticated, a gateway in between the mobile nucleus plus the cytoplasm. This is an extremely complex system and as a consequence tough to research in a mobile, so we use biomimetics. We reconstruct holes and after that insert individual things in the nucleopore complicated to check transport as a result of it at The only-molecule amount.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)